35 Results for "

Veratrum grandiflorum Loes.

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "Veratrum grandiflorum Loes." in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-N0836
CAS No.: 469-59-0
Synonyms: 11-Ketocyclopamine
Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM . Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties .
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3
3 Cited Publications
Cat. No.: HY-N4087
CAS No.: 66663-90-9
Platycodin D2 is an orally active triterpenoid saponin found in Platycodon grandiflorum. Platycodin D2 induces mitophagy in cancer cells through NIX, thereby activating the P21/CyclinA2 pathway and promoting cell senescence. Platycodin D2 induces mitochondrial dysfunction, enhances autophagy, inhibits hepatocellular carcinoma cell proliferation, and exhibits anti-tumor activity against multiple cancer cell types. Platycodin D2 promotes mRNA expression of T-bet, GATA-3, Th1 cytokines IL-2 and IFN-γ, and Th2 cytokines IL-4 and IL-10, enhances splenocyte proliferation, and acts as a vaccine adjuvant with low rabbit red blood cell hemolytic activity. Platycodin D2 induces mitochondrial ROS production, incomplete autophagy, and ferroptosis to inhibit breast cancer cell proliferation. Platycodin D2 can be used for the research of cancer, inflammation and immunology .
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3
3 Cited Publications
Cat. No.: HY-N6064
CAS No.: 66663-91-0
Polygalacin D (PGD) is a bioactive compound isolated from Platycodon grandiflorum with anticancer and anti-proliferative properties. PGD suppresses the expression of the IAP family of proteins including survivin, cIAP-1 and cIAP-2 and blocks the PI3K/Akt pathway by inhibiting the phosphorylation of GSK3β, Akt and the expression of PI3K. Polygalacin D induces apoptosis
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3
3 Cited Publications
Cat. No.: HY-N0588
CAS No.: 78763-58-3
Deapioplatycodin D is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity .
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2
2 Cited Publications
Cat. No.: HY-N3522
CAS No.: 237068-41-6
Platycoside E is a platycodigenin-type saponin isolated from the root of Platycodon grandiflorum with haemolytic activity and adjuvant potential. Platycoside E promotes the production of the sera OVA-specific IgG2a and IgG2b antibody in the ovalbumin (OVA)-immunized mice .
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1
1 Cited Publications
Cat. No.: HY-N3519
CAS No.: 67884-03-1
Platycodin D3 is a triterpenoid saponin that can be found in Platycodon grandiflorum. Platycodin D3 exhibits multiple activities including anti-inflammation, regulation of airway mucus secretion, improvement of asthmatic airway inflammation and remodeling, and inhibition of hepatitis C virus (HCV) replication. The IC50 value of Platycodin D3 against HCV NS5B RNA-dependent RNA polymerase is 8 μg/mL. Platycodin D3 can be used in studies related to asthma, hepatitis C virus infection and inflammatory diseases .
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1
1 Cited Publications
Cat. No.: HY-N3520
CAS No.: 67884-05-3
Deapi-platycodin D3 is a triterpenoid saponin from the roots of Platycodon grandiflorum .
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1
1 Cited Publications
Cat. No.: HY-N11911
CAS No.: 14320-81-1
Synonyms: (-)-Verazine
Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases .
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Cat. No.: HY-N6940
CAS No.: 19057-67-1
Synonyms: Progenin III
Prosapogenin A, a natural product from Veratrum, induces apoptosis in human cancer cells in vitro via inhibition of the STAT3 signaling pathway and glycolysis .
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Cat. No.: HY-N3521
CAS No.: 849758-42-5
Synonyms: Deapi-platycoside E
Platycoside G1, a natural product found in Platycodon grandiflorum, is a triterpenoid saponin. Platycoside G1 has potent antioxidant activities .
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Cat. No.: HY-N9377
CAS No.: 68051-23-0
Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation .
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Cat. No.: HY-N8630
CAS No.: 149183-75-5
Oleacein (Compound 9) is an ACE inhibitor that can be isolated from J. grandiflorum. Oleacein is orally active and can be used in the study of metabolic and cardiovascular diseases .
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Cat. No.: HY-128683
CAS No.: 23185-94-6
Purity:  ≥98.0%
Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound that may induce cyclopia in pregnant Mianyang embryos .
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Cat. No.: HY-N10647
CAS No.: 56317-09-0
Isoscutellarein 8-O-β-D-glucuronide is a flavonoid antioxidant, can be isolated from Theobroma grandiflorum seeds .
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Cat. No.: HY-N8922
CAS No.: 66779-34-8
Platycodin A is monoacetylated saponin compound isolated fromhe roots of Platycodon grandiflorum A. DC. .
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Cat. No.: HY-N8810
CAS No.: 917482-67-8
Target:  

Others

Research Areas:  

Others

Platycoside M1 is a A-ring lactone triterpenoid saponin that can be isolaoted from the roots of Platycodon grandiflorum. Platycosides are the main active constituents of P. grandiflorus with multiple pharmacological activities .
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Cat. No.: HY-107756
CAS No.: 143482-60-4
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

LOE 908 hydrochloride is a non-selective cation channel (NSCC) inhibitor .
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Cat. No.: HY-N12587
CAS No.: 314756-03-1
Platycoside F is a triterpenoid saponin compound that can be isolated from the roots of Platycodon grandiflorum .
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Cat. No.: HY-N11931
CAS No.: 200574-22-7
Grandivine A is a steroid alkaloid isolated from Veratrum grandiflorum .
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Cat. No.: HY-N11918
CAS No.: 469-60-3
Target:  

Others

Jervinone is a metabolite of the Veratrum alkaloid, which can be isolated from the mold Cunninghamella echinulata .
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